Hello Suwandi,
I would recommend preparing and testing the necessary recipients and filters in test systems first. If that works fine I'd apply them to production during business hours which are not peak hours. Reason is that they're in effect immediately, so you can be in the system and closely monitor if the prioritization works properly. You'll have to apply it to production at some time, anyway, so better it is in a weaker business hour where you can monitor it. I'd also prefer morning hours, since there is enough time then to correct mistakes in case anything goes wrong.
I would not de-register anything, since it only blocks messages across the system. You know that with a simple deactivation of the filter you can return the system to previous state, so there is no reason for big stopping and de-registering action.
I recommend you convince your business of that opinion before you apply the filters, just to make sure.
Regards,
Jörg
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