Different Ship to in a sales order

My question is, when i create a sales order and i have 2 line items, is it possible for me to have a different Ship to party on the 2nd line item?

Example

Material Quantity Ship to party

T-AS1 5 T-S50A

T-AS2 1 T-S50B

Can i have to different ship to's in one sales order and how can i do that? becasue when i try that changing my 2nd item to a different SH it also changes the 1st item to same SH, i'm doing this at header level partner function, since i can't make changes at item level Partner function?

Any suggestion?