Open your message mapping and press F7 button to see if there is any error in mapping. If yes then first correct the error and then try to activate it. If no error and still you are facing the problem in activating the mapping then contact your BASIS team.
If the mapping check (F7) is not prompting any error/ warning then there should not be any reason why the mapping is not activated. I would again suggest that you contact Admin/ Basis guys for this.....since it is occuring for all the (correct) mappings
For me it seems some temp memory issue which can be resolved by first check if there is proper memory space left in the disk on server (check with basis) because some time the log files becomes so huge and they fill the database very rapidly and that creates such kind of problems.
And secondly you can try by restarting the J2EE server.
If you are getting this error while activating all mapping programs then there may be some problem with the server....in this case contact the server Admin/ Basis guys.
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